The human microbiome, particularly the gut microbiota, has been increasingly recognized for its profound impact on overall health, including ocular health. This abstract explores the intricate relationship between the gut microbiome and the eye, highlighting emerging research tha [....] » Read More
Aim: To consider the presentation, management options, and randomised controlled trials investigating submacular haemorrhage (SMH) secondary to neovascular age-related macular degeneration (AMD), with a focus on the use of tissue plasminogen activator (TPA) and pneumatic dis [....] » Read More
Several neurodegenerative diseases, including glaucoma, diabetic retinopathy, and age-related macular degeneration all involve retinal cell death. Neuroprotection is an important goal for the prevention and treatment of neurodegeneration. To this end, having reliable experimental [....] » Read More
Purpose: To investigate new intrastromal histological structures that develop after myopic human lenticular implantation in keratoconus with femtosecond laser–assisted small incision lenticule extraction (SMILE) surgery using transmission electron microscopy. Methods: Sixt [....] » Read More
Purpose: To evaluate the clinical characteristics and surgical outcomes of retinal detachment associated with atopic dermatitis. Methods: A retrospective investigation of clinical notes of 37 patients with retinal detachment associated with atopic dermatitis was conducted from J [....] » Read More
This study aims to assess the intraoperative experiences of patients undergoing a modified manual irrigation implantable collamer lens (MI-ICL) implantation technique in comparison to femtosecond laser small incision lenticule extraction (SMILE). A customized questionnaire, devel [....] » Read More
Objective: To evaluate the efficacy and safety of a single-incision intraocular lens (ICL) implantation technique with and without use of ophthalmic viscosurgical devices (OVDs), focusing on postoperative intraocular pressure (IOP) changes and visual outcomes. Methods: This stud [....] » Read More
Diabetic Retinopathy (DR) is the most common microvascular complication in Diabetic patients and the leading global cause of vision loss in working middle-aged adults. Exposure to hyperglycaemia over an extended period and duration of diabetes are the most common risk f [....] » Read More
Patients with haematological disorders can present with a wide range of symptoms some of which can be visually debilitating. Visual prognosis depends upon the severity, chronicity as well as time of presentation. These can be divided two different groups, first one due to disease [....] » Read More
Strabismus surgery is a common ophthalmic procedure aimed at correcting misalignment of the eyes, thereby improving binocular vision and aesthetic appearance. While generally safe and effective, the surgery is not without risks and potential complications. One of the most common [....] » Read More
Purpose: This study investigated the effects of coenzyme Q10 (CoQ10) and Trolox on the N-methyl-D-aspartate (NMDA) induced death of retinal cells in glaucomatous conditions in vivo, and its effect on retinoblastoma in vitro and in ovo. Methods: Wistar rats for in vivo and [....] » Read More
Background: Rhegmatogenous retinal detachment (RRD) is essentially a tear in the retina leading to vitreous humor accumulation behind it. Despite lacking guidelines contraindicating vaginal delivery for RRD risk, many doctors may recommend cesarean sections due to reported [....] » Read More
Objectives: To illustrate the rapid visual recovery in a patient with MOG optic neuritis through early, high-dose corticosteroid intervention. Background: MOG optic neuritis is a severe inflammatory condition that can result in significant vision loss if not treated promptly. Hi [....] » Read More
Glaucoma is the leading cause of irreversible blindness worldwide, characterized by progressive vision loss due to the selective damage to retinal ganglion cells (RGCs) and their axons. Oxidative stress is generally believed as one key factor of RGCs death. Recently, necroptosis [....] » Read More
Purpose: To classify neovascularization in treatment naïve patients of PDR based on wide-field Optical Coherence Tomography – Angiography (OCT-A) Methods: All patients with PDR underwent detailed ocular examination including optical coherence tomography angiography (Z [....] » Read More
Aims/ Purpose: To report a patient with bilateral macular telangiectasia Methods: Patient came to the eye OPD with complaints of diminution of vision of both eyes Results: A 50 year old female came to the eye OPD with gradual, painless diminution of vision both eyes. She had no [....] » Read More
Two autopsy studies of optic nerves from 76 eyes of abusive head trauma (AHT) suspects demonstrated block of orthograde axonal transport in the lamina cribrosa (LC) in 94% of cases by APP-A4 immunohistochemistry (IHC).1,2 APP-A4 is the only currently available IHC marker f [....] » Read More
Purpose: To assess the diagnostic usefulness of retinal nonperfusion to classify eyes based on diabetic retinopathy (DR) severity on OCT angiography (OCTA) and determine whether wider field of view (FOV) OCTA protocols enhance the diagnostic usefulness of retinal nonperfusio [....] » Read More
Leber hereditary optic neuropathy (LHON) is a rare, maternally inherited mitochondrial genetic disease with a high unmet medical need. Three primary point mutations in the mtDNA are responsible for LHON in 90% of subjects: G3460A, G11778A and T14484C, located respectively in the [....] » Read More
Ocular injuries are kind of common ocular disorders sndvtheur timely treatment is very important to prevent any kind of visual loss the type of ocular injuries are: Perforating, Non perforating, Blunt, Finger nail injuries, Chemical, R t a related eye injuries, Sports related, H [....] » Read More
Vibrational Optical Coherence Tomography (VOCT) is a new non-invasive technique that provides an image based upon infrared light reflections from ocular components and simultaneous analysis of acoustic sound vibrations. The technology provides information to study the structure a [....] » Read More
Purpose: Large language models (LLMs) can accept text and image prompts as multimodal input. With implications for ophthalmology as a field, we evaluated the performance of several LLMs on relevant clinical vignette questions. Methods: We collected 100 cases of JAMA Ophthalmolog [....] » Read More
Purpose: Demographic representation in Diabetic Retinopathy Clinical Research (DRCR) studies is understudied and impacts the generalizability of results. This research aims to determine if the DRCR demographic data is representative of the United States (US) general diabetic popu [....] » Read More
Purpose: To evaluate the use of a novel software application downloadable on commercially available virtual reality (VR) headset in measuring ocular tropia. Methods: This study included 20 patients with ocular tropia. A masked ophthalmologist quantified the tropia using near and [....] » Read More
Purpose: To review consecutive cases of dislocated in the bag IOLs managed by the belt loop scleral fixation technique. Methods: Retrospective review of 71 consecutive cases managed using the belt loop scleral fixation scleral fixation technique. Results: 71 consecutive cases [....] » Read More
Introduction: This case study presents an adolescent patient with a complex ocular condition characterized by cystoid macular oedema (CMO) in both eyes (OU). The patient experienced significant diagnostic and management challenges, ultimately leading to the identification of [....] » Read More
Purpose: To evaluate the findings of optical coherence tomography angiography (OCTA) vessel density parameters in patients with primary open-angle glaucoma (POAG) and investigate both diagnostic performance of OCTA and correlations between control group and patients at diffe [....] » Read More
Introduction: This case study presents an elderly patient with a complex history of ocular conditions, including diabetic macular edema (DMO). The patient experienced significant complications leading to severe pain and vision loss, highlighting the challenges in diagnosing [....] » Read More
Introduction and Aims: Keratoconus is the most common primary ectasia, progressive corneal ectasia in which central or paracentral thinning of the corneal stroma occurs, leading to steepening of the corneal surface and irregular astigmatism. Management of this condition is largel [....] » Read More
Introduction: This study compared the outcomes of the Preserflo microshunt to trabeculectomy in patients diagnosed with primary open-angle glaucoma (POAG). The primary outcomes analyzed were post-operative intraocular pressure (IOP) and the medication burden following each surgic [....] » Read More
Introduction: Pars plana vitrectomy is a common surgical technique employed to allow access to the posterior segment to treat vitreoretinal conditions such as retinal detachments, macular holes and vitreous haemorrhage. NHS Grampian, as a health board responsible for over half a [....] » Read More
Leber’s hereditary optic neuropathy (LHON) is driven by mtDNA mutations affecting Complex I presenting as progres- sive retinal ganglion cell dysfunction usually in the absence of extra-ophthalmic symptoms. There are no long-term neuroprotective agents for LHON. Oral nicoti [....] » Read More
Background: Laser photocoagulation and/or intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections constitute the current standard treatment for retinopathy of prematurity (ROP). This systematic review and meta-analysis aimed to assess the efficacy and safety o [....] » Read More
Introduction: Myopia is a global problem with limited preventive measures including eye exercises, increasing outdoor time as well as low-dose atropine 0.01%. Pre-myopia is a refractive state in which the patient is at higher risk of developing myopia. The aim of this study is to [....] » Read More
Background: Pterygium is a common ocular surface disease. Recurrence is the greatest concern in the treatment of pterygium. Thus, a standardized and effective treatment modality with minimal risk for complications is needed for the management of pterygium. The aim of this systema [....] » Read More
Introduction: Myopia is the most common ocular condition worldwide, with a prevalence ranging from 24.32% to 35.81%, and its prevalence is expected to continue to increase globally. Moreover, myopia is associated with various serious ocular complications necessitating the need to [....] » Read More
Introduction: Vogt-Koyanagi-Harada (VKH) disease is rarely observed in preschool-aged children, and when it does occur, it typically presents with exudative retinal detachment during the acute phase. Treatment in this population commonly involves corticosteroids, immunosuppressan [....] » Read More
Purpose: To evaluate gender-specific differences in the etiology of uveitis through a comprehensive meta-analysis and systematic review, thereby illuminating how sex-based factors may influence disease prevalence, associated conditions, and potential underlying mechanisms. Metho [....] » Read More
Purpose: Herein, we compared the efficacy among the Ocular Trauma Score (OTS), Toddlers Ocular Trauma Score (TOTS), and Pediatric Ocular Trauma Score (POTS) for prognosis prediction in Indian children who had mechanical ocular conditions causing traumatic cataract. Methods: This [....] » Read More
Introduction: History has shown that restricted use of oxygen leads to higher mortality and neuro disability, whereas liberal usage is linked to ROP. With the upgradation of Neonatal intensive care unit (NICU) of a tertiary health care unit, the number of premature infants [....] » Read More
Design -Cross-sectional study Setting - Single center Participants - Ophthalmology trainees, OpenAI ChatGPT (GPT 3.5), Webmd, and Google Gemini Method Sixty Clinical Vignettes representating common ophthalmic conditions from Tertiary Care OPD were developed and a standardized pat [....] » Read More
Purpose: To illustrate the role of Rho kinase inhibitor, ripasudil in the setting of post traumatic corneal decompensation. Method: 32 years old male presented with blunt trauma to the left eye with corneal epithelial defect, stromal edema and Grade II hyphema. He was initially [....] » Read More
Introduction: Goldenhar Syndrome (Oculo-Auriculo-Vertebral Dysplasia, OAVS) Is A Rare, Congenital Disease Arising From The Abnormal Development Of The First And Second Branchial Arches. The Incidence Is Between 1:3500 And 1:5600, With A Male: Female Ratio Of 3:2. Method: We Retr [....] » Read More
A 22-year-old gentleman presented with a history of blurry vision and light sensitivity in both eyes. He had difficulty reading for the past two months. He denied any history of hyperhidrosis or anhidrosis. Clinical examination revealed that the basal diameter of both pupils was [....] » Read More
Purpose: The purpose of this study is to compare the incidence and characteristics of ocular trauma in children presenting during pandemic to those in pre-pandemic era. Method: In this study, we retrospectively reviewed the charts of all children with ocular injuries prese [....] » Read More
Background: We aimed to present the outcomes and complications following phacoemulsification cataract surgery complicated by anterior capsule tears. Methods: This study prospectively included patients who had phacoemulsification cataract surgery with anterior capsule tears. The [....] » Read More
Purpose: To investigate the differences in the effects of phacoemulsification, viscosynechiolysis, and Trabeculectomy on cases with a recent history of Acute Primary Angle Closure (APAC). Methods: Patients with cataracts, Peripheral Anterior Synechia (PAS), and a history of APAC [....] » Read More
Background: In this GP surgery in the past, patients were seen by both a GP doctor and optician prior to an ophthalmology referral. Due to the increased workload, referrals were then sent based purely on optician advice. The project was carried out to assess whether this pathway [....] » Read More
Background: Pan-retinal laser photocoagulation (PRP) is used in the management of diabetic retinopathy, aimed at preventing the growth of abnormal blood vessels in the retina and reducing the risk of vision loss. Absorption of laser occurs from pigment cells within the retina, wh [....] » Read More
Fundus photography is an arduous task using 90 diopters (D) in one hand and smartphone attached on an eyepiece of a slit-lamp biomicroscope. Similarly, with 20 D lens, the filming distance is adjusted by moving the lens or mobile forward or backward makes it difficult to adjust a [....] » Read More
Purpose: To educate beginner surgeons on dos and don'ts of performing lensectomy in microspherophakic subluxated lenses in children Setting/Venue: Pediatric Ophthalmology and Strabismus Department, Al-Shifa Trust Eye Hospital, Rawalpindi Method: A 2-year-old child with [....] » Read More
Background: Postburn contracture of eyelids may produce significant ocular morbidity, especially of the upper lid. Marked Lagophthalmos leads to exposure keratopathy followed by loss of vision. Purpose of the study is to evaluate how this kind of eyelid deformity can b [....] » Read More
Macular edema is a disorder when the macular region of the retina of the eye becomes edematous due to an accumulation of excess fluid. Macular edema manifestations can range from mild ones that hardly affect vision to severe ones that cause substantial visual impairment. Numerous [....] » Read More
Introduction: Retinal vasoproliferative tumors (VPTs) are rare benign lesions in the inferotemporal peripheral retina, appearing yellowish red on fundoscopy and containing vascular and glial components. While most VPTs occur without a known cause, a few are associated with c [....] » Read More
Background: In a society obsessed with physical fitness, the trend has recently extended to our ocular health. This study delves into the novel world of extreme eye exercises which have seen a surge in many fitness circles in the US, and analyses their purported benefits on visua [....] » Read More
The increasing workload placed on the glaucoma service in Ireland has led to the implementation of a virtual glaucoma service in the country’s leading eye hospital. Briefly, those with stable glaucoma who require monitoring attend on a regular basis for visual acuity, IOP m [....] » Read More
Background: Thermal pulsation system is a new used therapy that uses heat and massage to treat dry eye disease; thus, some trials have been published to compare it with the conventional treatment. The aim of this study is to conduct a systematic review and meta-analysis comp [....] » Read More
Mucous membrane pemphigoid (MMP) is a systemic cicatrizing autoimmune disease that primarily affects orifical mucous membranes, such as the conjunctiva, the nasal cavity, the oropharynx, and the genitalia. Ocular MMP (OcMMP) occurs when the conjunctiva is the primary site o [....] » Read More
Choroidal neovascularization (CNV) is a major cause of blindness in ocular fundus disease. The major defects of the current first-line anti-VEGF drugs for fundus disease are the high administration frequency and ocular complications. Meanwhile?about 40% of fundus disease patients [....] » Read More
Purpose: To investigate the relationship of retinal structure as measured on optical coherence tomography (OCT), to retinal function as assessed by electrophysiology, consisting of pattern (pERG) and full-field electroretinogram (ffERG), in patients with Immune-mediated Reti [....] » Read More
Diffuse unilateral sub acute neuro retinitis (DUSN) characterized by progressive unilateral visual impairment caused by nematode infestation in the retina. Presenting a case where mobile live worm present in macular detachment and its multimodal imaging and management. Cas [....] » Read More
Purpose: Aim is to give an overview of different lensectomy techniques which can be utilized in various scenarios of subluxated lenses in children. Method: We present various lensectomy techniques with or without intraocular lens implantation in five pediatric [....] » Read More
Stickler Syndrome is an uncommon frequently undiagnosed multisystem collagenopathy with significant genetic and phenotypic heterogeneity, a condition that carries a risk for significant ocular complications, ranging from severe myopia to retinal detachment and vision loss. System [....] » Read More
Background: Diabetic Retinopathy (DR) is a severe complication of diabetes that affects retinal blood vessels and can lead to blindness. The Middle East faces a significant public health challenge due to the high prevalence of DR among diabetics, with rates reaching up to 64% in [....] » Read More
Purpose: While AI chatbots are increasingly used for patient education, their effectiveness in providing accurate, comprehensive, and understandable information about ophthalmologic conditions remains understudied. We performed an observational, cross-sectional study to eval [....] » Read More
Title : Why was Leonhard Euler blind?
John David Bullock, Wright State University, United States
Leonhard Euler was one of the most eminent mathematicians of all time. In 1735, he developed right periocular swelling, partial loss of vision, and the onset of lifelong recurrent fevers from a heretofore-unknown affliction. Three years later, he developed an infection in the rig [....] » Read More
Title : Developing resilience-based treatments for glaucoma
Simon John, Columbia University, United States
We use mice to determine molecular mechanisms that contribute to intraocular pressure (IOP) elevation and glaucoma. Glaucoma is a common neurodegenerative disease that kills retinal ganglion cells. Elevated IOP is an important, causative risk factor for developing glaucoma. I wil [....] » Read More
Title : Monovision cataract surgery made simple
Shadrokh Nabili, University Hospitals of Morecambe Bay NHS Foundation Trust, United Kingdom
Background: The demand for presbyopia-correcting IOLs (intraocular lenses) at the time of cataract surgery is increasing. An alternative to implanting these lenses is monovision cataract surgery. Although it has limitations, it may be offered to patients as an option. This i [....] » Read More
Title : Mast cells in infllammation: Role of cytokines
Pio Conti, University of Chieti, Italy
Mast cells (MCs) originate from CD34+/CD117+/CD13+ pluripotent hematopoietic stem cells and they express the c-Kit receptor (c-Kit-R) which regulates their proliferation and sustains their survival, differentiation, and maturation. MCs are immune tissue cells derived from bone ma [....] » Read More
Title : Visual snow syndrome: Unraveling a mysterious visual disorder
Oliwia Kamieniecka, Medical Univeristy of Warsaw, Poland
Visual Snow Syndrome (VSS) is a neurological disorder characterized by persistent visual disturbances, most notably a continuous “visual snow” or static across the visual field, which can profoundly impact quality of life. In addition to the primary symptom of visual [....] » Read More
Title : The Glaucoma Drainage Device (GDD) experience in a tertiary referral centre in Ireland over the past six and a half years
Liam Bourke, Irish College of Ophthalmology, Ireland
Background: The control of intraocular pressure (IOP) is a cornerstone of treatment for glaucoma. Glaucoma drainage devices (GDDs) are increasingly used in cases with uncontrolled IOP, despite maximum medical therapy. Recent trials demonstrated that the Baerveldt implant ach [....] » Read More
Title : GB10, a best-in-class antibody fusion protein targeting VEGF/Ang-2, exhibits promising therapeutic efficacy for neovascular eye diseases
Suofu Qin, Kexing Biopharm Co., Ltd., China
In clinical practice, anti-vascular endothelial growth factor (VEGF) therapies have been successfully applied to patients with neovascular eye diseases. However, unmet clinical needs have not yet been fully addressed, as about 20% of patients do not response to anti-VEGF mo [....] » Read More
Title : Early retinal microcirculation loss in non-functioning pituitary adenomas before visual field defect by WF SS-OCTA
Chong Tang, The First Affiliated Hospital of Chongqing Medical University, China
Purpose: To evaluate the early retinal microcirculation alteration in non-functioning pituitary adenomas (NFPA) before visual field defects (VFD) by wide-field swept-source optical coherence tomography (WF SS-OCTA) Methods: 82 NFPA patients without VFD and 82 age-matched, s [....] » Read More
Title : ATP-P2X7R-mediated microglia senescence aggravates retinal ganglion cell injury in chronic ocular hypertension
Min Ji, Affiliated Hospital of Nantong University, China
Background: Dysfunction of microglia during aging affects normal neuronal function and results in the occurrence of neurodegenerative diseases. Retinal microglial senescence attributes to retinal ganglion cell (RGC) death in glaucoma. This study aims to examine the role of A [....] » Read More
Title : Autophagy impairment-derived SQSTM1 accumulation promotes ferroptosis in corneal epithelial cells through ACSL4 in dry eye
Bowen Wang, Zhongshan Ophthalmic Center, China
Purpose: To reveal the function of autophagy impairment-derived Sequestosome-1 (SQSTM1) in inducing ferroptosis in experimental dry eye model and investigate the underlying mechanism. Methods: To induce dry eye animal model, 8-week C57BL/6 mice were subcutaneously injected with [....] » Read More
Title : Effect of Nd: YAG capsulotomy on retina
Chong Tang, The First Affiliated Hospital of Chongqing Medical University, China
Purpose: To evaluate the effect of neodymium: yttrium aluminium garnet (Nd: YAG) laser capsulotomy on retinal thickness and microcirculation by wide-field swept-source optical coherence tomography (WF SS-OCTA). Methods: 62 eyes of 62 patients who had posterior capsule opacificat [....] » Read More
Title : The effectiveness of surgical treatment of terson syndrome
Anna Rusanovskaia , State Budgetary Healthcare Institution, Russian Federation
Terson's syndrome (hemorrhagic oculocerebral syndrome) is a vitreal, preretinal, subgialoid or subretinal hemorrhage associated with acute subarachnoid, intracerebral hemorrhage, or traumatic brain injury. The clinical picture is characterized by a sharp mono or bilateral los [....] » Read More
Title : Surgical treatment of chronic macular hole by hydraulic mobilization of the central parts of the retina
Anna Rusanovskaia , State Budgetary Healthcare Institution, Russian Federation
Objective: to evaluate the safety and effectiveness of the technique of hydraulic mobilization of the central parts of the retina in the surgical treatment of chronic macular ruptures. Materials and methods: 11 patients (11 eyes) with chronic macular rupture were under obse [....] » Read More
Title : Roth spots serving as a clue to underlying acute myeloid leukemia
P Muralidhar, AIIMS Mangalagiri, India
Acute myeloid leukemia is one of the causes of Roth spots. We report here a female patient in her early thirties, of Asian origin, presenting to our ophthalmology outpatient clinic with complaints of decreased visual acuity in the Right eye along with generalized weakness, palpit [....] » Read More
Title : Effect of artificial tears on K reading in patients with chronic dry eye disease
Doaa Grew, Benghazi Eye Hospital, Libyan Arab Jamahiriya
Objective: The aim of this study was to evaluate the effect of artificial tears on astigmatism and keratometric (K) readings in patients with chronic dry eye disease. Specifically, we sought to determine whether artificial tears improve astigmatism, the prevalence of astigmatism [....] » Read More
Title : Daily artificial tears as a preventive measure for dry eye syndrome in medical students: A systematic review and meta-analysis
Nodira Makhmudova, Akfa Medline University Hospital, Uzbekistan
Purpose: To determine the efficacy of the daily artificial tears usage as a dry eye syndrome prophylaxis among medical students, who are at increased risk due to lifestyle factors. Methods: We performed a systematic review and meta-analysis following the Preferred Reporting Item [....] » Read More
Title : Effect of combination of anti-VEGF and corticosteroid use in two patients with early-onset central retinal vein occlusion
Javokhirbek Ravshanbekov, Akfa Medline University Hospital, Uzbekistan
Purpose: Central Retinal Vein Occlusion (CRVO) is an uncommon condition in young adults that can lead to severe visual impairment if untreated. This study evaluates the treatment outcomes of two young male patients with CRVO who underwent a combination of intravitreal anti-V [....] » Read More
Title : Atopy and its role in the development and progression of keratoconus: A systematic review and meta-analysis
Mokhiryam Aliyeva, Akfa Medline University Hospital, Uzbekistan
Purpose:Progressive condition which is characterized by corneal thinning,distorted astigmatism and impaired vision is called keratoconus (KC). Development of a disease is often associated with genetic predisposition and environmental factors. This study seeks to investigate the r [....] » Read More
Title : Anti-inflammatory properties of omega-3 fatty acids and its clinical significance in the treatment of dry eye syndrome
Jamshid Mamatov, Akfa Medline University Hospital, Uzbekistan
Purpose: to evaluate the effectiveness of nutritional omega-3 fatty acid supplementation in the management of dry eye disease (DED). We focused on the anti-inflammatory properties of omega-3 and its impact on the symptoms and signs of DED, especially in patients with meibom [....] » Read More
Title : Effect of optic nerve sheath fenestration on visual function, neurological status, and oct metrics in idiopathic intracranial hypertension
Reza Nabie, Tabriz University of Medical Science, Iran (Islamic Republic of)
IIH is defined as increased intracranial pressure (ICP) without an identifiable cause, which results in optic nerve damage and potential vision impairment. The purpose of this study was to evaluate the efficacy of optic nerve sheath fenestration (ONSF) in improving visual outcome [....] » Read More
Title : Characteristics of peripheral retinal refraction and its role in children with different refractive states
Yanhua Wang, Shanxi Aier Eye Hospital, China
Objective: Peripheral retinal refraction plays a crucial role in myopia, but the specific mechanism is not clear. We refined the retinal partitions to explore the characteristics of peripheral retinal refraction in emmetropic, low and moderate myopic children aged 6 to 12 years o [....] » Read More
Title : Short-term efficacy of defocus spectacle lenses in controlling myopia in children using multispectral refracion topographer
Yaning Chen, Baoding Aier Eye Hospital, China
Purpose: The aim of this article was to investigate the changes in peripheral retinal defocus in children wearing defocus spectacle lenses and to evaluate its relationship with axial growth. Methods: A total of 200 myopic children aged 8-14 who visited our hospital in [....] » Read More
Title : Efficacy of varenicline solution nasal spray (VNS) 0.03mg on signs and symptoms of dry eye disease: ONSET 1, ONSET 2, and MYSTIC trials
Patrick Vollmer, Core, Inc, United States
Purpose: Dry Eye Disease (DED) is a multifactorial, chronic disease characterized by a persistently unstable and/or deficient tear film leading to visual discomfort or impairment, with varying degrees of neurosensory abnormalities, inflammation, and ocular surface epitheliopathy. [....] » Read More
Title : An overview of deep-learning enabled microbial keratitis classification
Savini Hewage, Whittington Health NHS Trust, United Kingdom
Infectious keratitis (IK) is the fifth leading cause of blindness globally. Gold-standard diagnostic techniques of microscopy, cultures and sensitivity from corneal scrapes are limited by low sensitivity, invasiveness, and time lag for identifying causative organisms. This revie [....] » Read More
Title : Hyperbaric oxygen therapy for crao in a pediatric patient: A case of sudden unilateral visual loss Post-DSA of an arteriovenous malformation
Carmen N Plaza Mejias, UPR-SOM, Puerto Rico
Central retinal artery occlusion (CRAO) is an ophthalmic emergency that typically presents as a sudden, profound, and painless monocular visual loss, potentially leading to permanent blindness. While rare in the pediatric population, the etiology in children can differ from that [....] » Read More
Title : Evaluation and implementation of a probing model for nasolacrimal duct probing simulation: A pilot study in ophthalmology residents
Saralee Theerakulpisut, Prince of Songkla university, Thailand
Introduction: Congenital nasolacrimal duct obstruction (CNLDO) is a leading cause of epiphora in children, commonly treated through probing. Traditional training methods, which involve hands-on practice with pediatric patients, face limitations due to ethical concerns and limited [....] » Read More
Title : An interesting case of CMV anterior uveitis
Meghna Ghodarope, Santosh Medical College and Hospital, India
Cytomegalovirus (CMV) anterior uveitis is the predominant ocular manifestation of CMV in immunocompetent individuals, typically arising from local reactivation of latent CMV and usually presents unilaterally. Characterized by mild anterior chamber inflammation, elevated intraocul [....] » Read More
Title : Case report: Orbital trauma mimicking globe rupture: A case of preserved vision
Piyush Jain, Maharaja Krushna Chandra Gajapati Medical College, India
This case report describes a 38-year-old male who presented with significant orbital trauma following an injury by a wooden object. Despite a concerning CT scan suggesting right globe rupture, surgical exploration revealed an extraconal foreign body with an intact globe. This r [....] » Read More
Title : Retinal injury from accidental laser exposure: A case report
Muhammad Saad Abbas, Aga Khan University, Pakistan
A 31-year-old female dermatologist reported visual disturbances, including haziness and floaters in her left eye, after accidental exposure to a picosecond laser. Initial ophthalmologic evaluation revealed a visual acuity of 20/25 in both eyes, with normal intraocular pressure an [....] » Read More
Title : Assessing GPT-4o and GPT-4 in answering and explaining ophthalmology exam questions from Taiwan’s medical licensing test
Chen Wei Lin, Chang Gung Memorial Hospital, Taiwan
Purpose: This study aims to evaluate and compare the performance of GPT-4o and GPT-4 in answering Taiwan's National Medical Licensing Examination ophthalmology questions from 2014 to 2023, focusing on both answer accuracy and explanation quality. Materials and Methods: A tot [....] » Read More
Title : Acute anterior uveitis induced by omidenepag isopropyl (Eybelis): A case report and literature review
Chen Wei Lin, Chang Gung Memorial Hospital, Taiwan
Purpose: Omidenepag Isopropyl, a non-prostaglandin selective EP2 receptor agonist, has been shown to effectively lower intraocular pressure (IOP) in glaucoma patients by increasing aqueous outflow through both conventional and uveoscleral pathways. First introduced in Japan [....] » Read More
Title : Protein and mineral malnutrition in military personnel and its association with dry eye syndrome
Jamshid Mamatov, Akfa Medline University Hospital, Uzbekistan
Military personnel are frequently faced with environmental challenges and operational demands.These barriers increase vulnerability to nutrient deficiencies including minerals and proteins imbalance. Such nutrient deprivation can make a disadvantageous impact on ocular wellness,e [....] » Read More
Title : Evaluating patient communication in the retinal unit at Moorfields eye hospital: A survey-based study on intravitreal injection therapy
Yasmin Adelekan Kamara, Moorfields, United Kingdom
Background: Intravitreal injection (IVI) therapy used in the management of exudative retinal diseases has expanded significantly following the introduction of anti-vascular endothelial growth factor (anti-VEGF) drugs. With an ageing population in the UK, the numbers of patients r [....] » Read More
Title : A case of waardenburg syndrome type 1 without deafness
Bright Owusu Prempeh, Anglican Eye Clinic, Ghana
Purpose: Waardenburg Syndrome is a congenital disease characterised by a white forelock with premature greying of the hair, broad nasal root, eyes of different colours due to heterochromia irides, bushy eye brows with synophrys, hypertelorism, depigmented dermal patches and [....] » Read More
Title : Bilateral medial rectus resection for recurrent exotropia
Shadi Farabi Maleki, Tabriz University of Medical Science, Iran (Islamic Republic of)
Purpose: Bilateral lateral rectus (BLR) muscle recession is a common treatment for exotropia; however, under-correction and recurrence remain significant challenges. This retrospective study aimed to evaluate the outcomes of bilateral medial rectus (BMR) resection in patient [....] » Read More