Aim: To provide an educational update on the presentation and management of common vitreoretinal disease. Methods: Lesions covered include peripheral retinal degeneration, posterior vitreous detachment (PVD), retinal breaks, retinal detachment, macular hole and epiret [....] » Read More
Leber Hereditary Optic Neuropathy (LHON) is a rare, maternally inherited mitochondrial genetic disorder characterized by sudden, painless vision loss. The disease has a significant unmet medical need and is primarily caused by three mitochondrial DNA point mutations: G3460A, G117 [....] » Read More
Abstract: Several neurodegenerative diseases, including glaucoma, diabetic retinopathy, and age-related macular degeneration all involve retinal cell death. Reliable experimental models of such diseases are important for developing novel therapeutic strategies and for assessing t [....] » Read More
Topic: This scoping review synthesizes existing evidence on the ocular health status of homeless or marginally housed (HMH) adults, highlighting the prevalence of visual impairment, ocular pathologies, and barriers to accessing care. Clinical Relevance: HMH adults are disproport [....] » Read More
Introduction: This case report discusses a patient presenting with elevated intraocular pressure (IOP) unresponsive to oral or intravenous treatment, necessitating urgent cyclodiode intervention. Initial investigations revealed the possibility of either uveal melanoma or supracho [....] » Read More
Introduction: NHS cataract service delivery has been increasingly challenged by rising demand, resources constraints, the pandemic, and the expansion of independent sector providers (ISPs). This study aims to assess whether there has been a shift towards managing more non-routine [....] » Read More
Background Non-infectious uveitis encompasses a spectrum of intraocular inflammatory diseases involving the uveal tract, retina, vitreous, and optic nerve. Complications such as cystoid macular oedema (CME), cataract, and secondary glaucoma contribute to nearly 10% of legal blin [....] » Read More
Aim: To evaluate the impact of the Iluvien implant on patient-reported quality of life in individuals with macular oedema. This study assessed changes in health status across functional, psychological, and visual domains using the EQ-5D-5L and EQ-VAS instruments. Methods: Semi [....] » Read More
Introduction Big Data and AI are transforming ophthalmology, particularly in the early detection of diabetic retinopathy (DR). Leveraging vast datasets and machine learning, these technologies enhance diagnostic accuracy and accessibility. However, ethical concerns regarding da [....] » Read More
Abstract Optogenetic therapy holds great potential for treatment of late-stage photoreceptor degenerative diseases. However, clinical translation of such therapeutic candidates is usually impeded by inconsistency in evaluation of visual function between preclinical models and cl [....] » Read More
Title : Rare and interesting case of Goldenhar’s syndrome in a 3 years old male child
Gowhar Ahmad, Florence Hospital Srinagar, India
It was an Austrian ophthalmologist, Maurice Goldenhar, who in 1850 first described a syndrome complex characterized by congenital presence of limbal dermoid with congenital associated presence of preauricular skin tag or appendage. Sometimes, there is presence of squint, anophth [....] » Read More
Title : Targeting immunological pathways in Behcet's Uveitis
Hashim Butt, Bolton Royal Hospital, United Kingdom
Behçet’s disease (BD) is a rare, chronic, multisystem inflammatory disorder that primarily affects blood vessels of all sizes. Clinically, it is characterised by recurrent oral and genital ulcers, skin lesions, and ocular involvement, particularly uveitis, which can [....] » Read More
Title : Evaluating the quality and readability of AI chatbot responses to frequently asked questions on basal cell carcinoma: Implications for patient education and digital health communication
Arrane Selvamogan, Leicestershire Partnership NHS Trust, United Kingdom
Background: Artificial intelligence (AI)-powered chatbots are increasingly used to deliver health information, providing real-time, accessible responses to patient queries. Concerns persist about the clarity, accuracy, and credibility of AI-generated medical content, especially [....] » Read More
Title : Evaluating the quality and readability of AI-generated ophthalmic surgery education: A four-model comparison
Arrane Selvamogan, Leicestershire Partnership NHS Trust, United Kingdom
Background: Artificial intelligence (AI) tools, particularly large language models (LLMs), are increasingly utilised to provide health information, with patients seeking simplified explanations of surgical procedures. In ophthalmology, the readability and reliability of AI-gener [....] » Read More
Title : Subthreshold micropulse laser for residual subretinal fluid after vitrectomy in myopic tractional maculopathy? A randomized controlled trial
Zhang Xifang, Beijing Tongren Hospital, China
Myopic tractional maculopathy (MTM) represented by macular schisis is the main cause of visual impairment in high myopia patients. Therapeutically, vitrectomy can make the retina more elastic and easier to reattach by removing the vitreous cortex and/or the internal limiting memb [....] » Read More
Title : Ahmed glaucoma valve implantation vs. trabeculotomy as initial intervention for primary congenital glaucoma-long term follow-up
Elizabeth Tal Mushinski, Ben-Gurion University of the Negev, Israel
Purpose: To compare the outcomes between initial AGV implantation and trabeculotomy in children with primary congenital glaucoma (PCG). Patients and Methods: This retrospective cohort study was conducted on patients with PCG who underwent either trabeculotomy or AGV implantation [....] » Read More
Title : Analysis of peripapillary and macular blood flow in non-arthritic ischemic optic neuropathy with optic coherence tomography angiography
Gunash Niftiyeva, Hacettepe University Hospital, Turkey
Our aim in this study is to evaluate peripapillary and macular blood flow in patients diagnosed with non-arteritic ischemic optic neuropathy (NA-AION) and to compare them with the healthy eyes of the patients and healthy individuals. 20 patients older than 50 years of age diagno [....] » Read More
Title : The effect of an eyelid-warming device (Blephasteam) on intraocular pressure in patients with meibomian gland dysfunction
Patima Sujipinyo, Chiang Mai University, Thailand
Background: This randomized cross-over study focused on the use of an eyelid-warming device (Blephasteam®) which can monitor heat therapy during a period of time in an enclosed environment as a treatment of meibomian gland dysfunction (MGD). According to the inconclusive asso [....] » Read More
Title : Hitting the trifecta-ocular syphilis
Lisa Sunny, Aravind Eye Hospital, India
26 year old male presented to the outpatient department of our clinic with complaints of blurred vision in right eye for past 1 week. It was insidious in onset, and gradual without any associated redness or pain . There was no history of any ocular or head trauma. He did not have [....] » Read More
Title : Optical coherence tomography angiography of retinal microvasculature in diabetic eyes without retinopathy undergoing cataract surgery: A prospective observational study
Yeddula Venkata Rohith Reddy, Sri Devaraj Urs Medical College, India
Background: In diabetic patients without retinopathy, unexplained suboptimal visual recovery following cataract surgery remains a clinical challenge. While retinal microvascular alterations may exist prior to visible diabetic retinopathy (DR), their subclinical detection and pro [....] » Read More
Title : The emotional retina: Revealing invisible suffering through retinal vascular biomarkers in young adults using octa — A new era in Psych-Ophthalmology
Yeddula Venkata Rohith Reddy, Sri Devaraj Urs Medical College, India
Purpose: To investigate whether the human retina can serve as a non-invasive mirror of emotional suffering, even in individuals with perfect vision. This study introduces the concept of the “Emotional Retina” and explores retinal vascular changes assoc [....] » Read More
Title : Corneal blindness can be prevented-right decision, right action is the need of the hour
Kandagadla Jyoti, MTMC, India
Introduction Corneal blindness accounts to 3.2 to 5.1 % of all cases of blindness worldwide. A wide variety of diseases and conditions can cause corneal blindness. In this presentation I would like to summarise the various causes, methods to prevent them and the role of op [....] » Read More
Title : Results of operation klaro phase 2: Extent of Low-Vision Disability (LVD) in rural Mindanao Philippines
Archie D Bunani, MISSION FAMILY INFIRMARY, Philippines
Background The risk of developing low-vision disability (LVD) in all population begins in the womb as the fetus develops its neurobiology. There has been no single recommendation for the screening of LVD among infants, children, and adults as attention to this case in the [....] » Read More
Title : SUMOylation is a translatable target in hypoxic MNPs regulating retinal vasculopathy
Xufang Sun, Huazhong University of Science and Technology, China
Retinal vasculopathies pose devastating threat to human health. While anti-VEGF therapy situates the first-line treatment for patients, the clinical efficacy is limited by suboptimal response and potential risks raised by the long-term high-dosage use. Neurovascular unit (NVU) un [....] » Read More
Title : The effect of low hypermetropia correction and office-based orthoptic training on binocular vision parameters in children with convergence insufficiency
Agnieszka Rosa, Orticus Center for the Treatment of Strabismus and vision Disorders, Poland
Purpose: The study aimed to determine the effect of low hypermetropia correction and orthoptic exercises on binocular visual function and vision parameters in children with symptomatic convergence insufficiency. Methods: The study was designed a prospective, randomized intervent [....] » Read More
Title : Characteristics of eyesight functioning and vision abnormalities in STXBP1 synaptopathy patients
Agnieszka Rosa, Orticus Center for the Treatment of Strabismus and vision Disorders, Poland
Introduction: An attempt was made to describe the specificity of children's visual functioning with developmental epileptic encephalopathy resulting from mutations in the STXBP1 gene. Methods: The study included 26 patients from the Polish STXBP1 population (11 men and [....] » Read More
Title : A report of periocular epidermodysplasia verruciformis lesions in a young adult with a review of literature
Satheesh Solomon T Selvin, Christian Medical College, India
Epidermodysplasia Verruciformis (EV) is a rare autosomal recessive dermatological genetic disorder of the immune system, primarily affecting the extremities of the limbs. Presentations with involvement of the face and other regions of the body is rare, especially the periocular r [....] » Read More
Title : Think twice: A case of a glial heterotopia mistaken for a dacryocystocele in a 2-year old female from the Philippines
Louise S Aguirre, Northern Mindanao Medical Center, Philippines
A dacryocystocele is a rare congenital disorder characterized by a unilateral, translucent bluish cystic mass below the medial canthus. Patients typically present with watering of the affected eye. This paper describes a 2 year old female who came in with a mass below the right m [....] » Read More