Behçet’s disease (BD) is a rare, chronic, multisystem inflammatory disorder that primarily affects blood vessels of all sizes. Clinically, it is characterised by recurrent oral and genital ulcers, skin lesions, and ocular involvement, particularly uveitis, which can [....] » Read More
Introduction: To explore the correlation between acute anterior uveitis (AAU) and undiagnosed or poorly controlled diabetes mellitus (DM), and to emphasise the importance blood sugar testing in Eye Emergency in case of Uveitis Case series: This case series describes four [....] » Read More
Topic: We reviewed the use of minimal clinically important difference (MCID) or related terminology, as well as the analysis of clinical relevance in ophthalmology trials, both in study design and in result reporting. Clinical relevance: MCID is defined as “the smallest [....] » Read More
A 75-year-old woman presented to her GP with a one-month history of bilateral lower leg livedo reticularis extending to the thighs, accompanied by burning dysaesthesia of the soles, weight loss, fatigue and night sweats. Weeks later, she re-presented with a necrotic ulcer on the [....] » Read More
Purpose: This umbrella review evaluates the efficacy, safety, functional, and anatomical outcomes of internal limiting membrane (ILM) peeling versus no peeling in idiopathic epiretinal membrane (iERM) surgery. Methods: A systematic search of PubMed/MEDLINE, Scopus, Web of Scie [....] » Read More
Our aim in this study is to evaluate peripapillary and macular blood flow in patients diagnosed with non-arteritic ischemic optic neuropathy (NA-AION) and to compare them with the healthy eyes of the patients and healthy individuals. 20 patients older than 50 years of age diagnos [....] » Read More
Purpose: To investigate the predictive factors for postsurgical visual prognosis in patients with vitreomacular traction (VMT). Methods: This retrospective study enrolled 31 eyes from 29 patients who underwent vitrectomy for idiopathic VMT with a follow-up period of ≥ 3 m [....] » Read More
Background and aims: To address the limitations of conventional postoperative eye drop regimens following cataract surgery, we developed an acid-sensitive prodrug-based microcrystals (MCs) of dexamethasone (SKD) for sustained anti-inflammatory therapy via subconjunctival (SC [....] » Read More
Background and aims: To address the limitations of conventional postoperative eye drop regimens following cataract surgery, we developed an acid-sensitive prodrug-based microcrystals (MCs) of dexamethasone (SKD) for sustained anti-inflammatory therapy via subconjunctival (SC [....] » Read More
Purpose: To assess potential changes in lens capsule biomechanical and electron microscopic appearance after staining with indocyanine green (ICG). Setting: Department of Ophthalmology, Beijing Tongren hospital, Capital Medical University, China. Design: Experimental s [....] » Read More
Objective: This study aims to report a rare case of sudden iris metastasis in an 3-year-and-8-month-old child with neuroblastoma during the post-primary tumor resection and chemotherapy period. Through clinicopathological comparative analysis, it explores the clinical charac [....] » Read More
26 year old male presented to the outpatient department of our clinic with complaints of blurred vision in right eye for past 1 week. It was insidious in onset, and gradual without any associated redness or pain . There was no history of any ocular or head trauma. He did not have [....] » Read More
Uveitic glaucoma affects uveitis patients due to Inflammation , neovascularization or Corticosteroid-induced glaucoma from treatment of uveitis.1 There were three eyes (three patients) of Uveitic glaucoma were managed by a glaucoma drainage device. At the 12-month follow-up visit [....] » Read More
The rising global burden of vision-threatening conditions highlights the need for scalable, accessible, and accurate screening tools. RetinX is an AI-powered mobile application developed to address this challenge by enabling the early detection and monitoring of ocular and system [....] » Read More
Intra operative surprises requiring on the spot decision making and adaptability make pediatric cataract surgery challenging. We present a case of pediatric cataract with iris and lens coloboma planned for cataract extraction with primary posterior capsulorhexis with intra ocular [....] » Read More
Study design: Retrospective comparative study Purpose: To evaluate the efficacy of two types of vision therapy for amblyopia in children with anisometropic amblyopia who had previously undergone patching therapy. Methods: Children 5-18 years of age diagnosed [....] » Read More
The coexistence of ectopic pupil and microcoria is a rare and, to our knowledge, previously unreported postoperative sequelae of primary congenital cataract surgery. A 5-year-old boy who was operated elsewhere for congenital cataract at 1 year of age presented to us with an ectop [....] » Read More
Purpose: Phakic IOL implantation is a viable option for refractive errors with promising visual outcomes. However, despite meticulous pre-operative planning and calculations, one may encounter unpredictable outcomes post phakic IOL implantation. At such times, it becomes difficul [....] » Read More
Purpose: Post-LASIK epithelial ingrowth (PLEI) is an uncommon complication that is usually asymptomatic and does not warrant treatment. However, it can cause significant refractive error, dreadful complications, and flap melt in some patients. This is a prospective case seri [....] » Read More
We present 2 similar cases of Toxoplasma Retinochoroiditis. A 32-year-old female and 21 year old male, who presented with sudden painless unilateral diminution of vision. On examining the female, her BCVA in affected right eye was 6/36 N36, the anterior segment was unremarkable, [....] » Read More
Background: This randomized cross-over study focused on the use of an eyelid-warming device (Blephasteam®) which can monitor heat therapy during a period of time in an enclosed environment as a treatment of meibomian gland dysfunction (MGD). According to the inconclusive asso [....] » Read More
Objective: To identify the clinical characteristics and prognosis of patients with primary ocular adnexal lymphoma (OAL) in southern Thailand. Methods: A retrospective case series in a tertiary-care of 110 patients with OALs between January 2013 and June 2024 w [....] » Read More
Background: Hypertension may lead to target organ damages associated with both microvascular and macrovascular complications. Retinal photography is a simple non-invasive tool that may detect retinal microvascular abnormalities in hypertensive patients, which may indicate a hig [....] » Read More
Purpose: To evaluate the efficacy and safety of topical insulin in promoting corneal epithelial healing in cases of refractory persistent epithelial defects (PEDs) unresponsive to conventional therapies. Design: Prospective interventional case series. Methods: Twenty e [....] » Read More
Background: Intermediate-stage dry age-related macular degeneration (AMD) remains a major cause of irreversible central vision loss, with no approved treatments capable of restoring photoreceptors. Regenerative strategies—such as stem cell delivery and allogenic biomaterial [....] » Read More
Background: Intermediate-stage dry age-related macular degeneration (AMD) remains a major cause of irreversible central vision loss, with no approved treatments capable of restoring photoreceptors. Regenerative strategies—such as stem cell delivery and allogenic biomat [....] » Read More
Objective: This study summarizes emerging clinical evidence supporting the use of Automatic Dual Rotational Risley Prisms (ADRRPs) as a novel platform for binocular vision assessment and vergence training, with particular emphasis on its applicability to convergence insufficiency [....] » Read More
Purpose: To study the clinical presentation, outcomes, and factors affecting the final visual outcome of Vogt-Koyanagi-Harada (VKH) disease in the pediatric age group. Methods: Pediatric patients who were diagnosed with VKH at King Khaled Eye Specialist Hospital (KKESH) betwee [....] » Read More
Backgroud: Orthokeratology has been proved to temporarily alter the equivalent sphere. On condition that orthokeratology combined with atropine 0.01% +brinzolamide tarding myopia deserves attention. Purpose: A comparative study was performed to evaluate the effective [....] » Read More
Purpose: The purpose of this study was to investigate the human eye’s recognition of moving objects of various colors in different spaces (altitude, dark background and oxygen concentration). Through detailed analysis of the three major factors, namely, altitude, angular ve [....] » Read More
The accurate classification of diabetic types from ocular surface images remains a major challenge due to subtle feature variations and overlapping visual patterns among different diabetic categories. To address this issue, this study introduces a robust deep learning framework t [....] » Read More
Purpose: To investigate color discrimination performance and its relationship with lens opacity in cataract patients under daytime and nighttime conditions. Methods: Color discrimination of seven hues (red, orange, yellow, green, cyan, blue, and purple) was assessed in 68 cata [....] » Read More
Purpose: To compare the efficacy of manual versus software - based vision therapy in young adults (aged 18-35 years) with accommodative insufficiency. Methodology: This was a single centre non-blinded (open label) RCT taking young adults (aged 18-35 years) diagnosed with [....] » Read More
A 43- year female presented with diminished vision in her right eye since 5 months (visual acuity of FCCF) associated headache. On examination she had grade 5 disc edema with peripapillary fluid and partial macular star. Fellow eye was clinically normal. All investigations were n [....] » Read More
This is the case report of a 31-year-old male, known case of Nephrotic syndrome, secondary to Membranoproliferative glomerulonephritis(MPGN) diagnosed on kidney biopsy referred for fundus examination. On examination, he had a BCVA of 6/6 in both the eyes with normal intraocular p [....] » Read More
Background The risk of developing low-vision disability (LVD) in all population begins in the womb as the fetus develops its neurobiology. There has been no single recommendation for the screening of LVD among infants, children, and adults as attention to this case in the [....] » Read More
Purpose: The study aimed to determine the effect of low hypermetropia correction and orthoptic exercises on binocular visual function and vision parameters in children with symptomatic convergence insufficiency. Methods: The study was designed a prospective, randomized intervent [....] » Read More
Introduction: An attempt was made to describe the specificity of children's visual functioning with developmental epileptic encephalopathy resulting from mutations in the STXBP1 gene. Methods: The study included 26 patients from the Polish STXBP1 population (11 men and [....] » Read More
Epidermodysplasia Verruciformis (EV) is a rare autosomal recessive dermatological genetic disorder of the immune system, primarily affecting the extremities of the limbs. Presentations with involvement of the face and other regions of the body is rare, especially the periocular r [....] » Read More
Background: Glaucoma, the leading cause of irreversible blindness, demands early diagnosis and consistent monitoring, which remain difficult due to the subjectivity of traditional assessments. Retinal fundus imaging combined with deep learning offers a promising avenue for the ob [....] » Read More
A dacryocystocele is a rare congenital disorder characterized by a unilateral, translucent bluish cystic mass below the medial canthus. Patients typically present with watering of the affected eye. This paper describes a 2 year old female who came in with a mass below the right m [....] » Read More
Aim: To provide an educational update on the presentation and management of common vitreoretinal disease. Methods: Lesions covered include peripheral retinal degeneration, posterior vitreous detachment (PVD), retinal breaks, retinal detachment, macular hole and epire [....] » Read More
Astigmatism management is one of the two main objectives of refractive cataract surgery, with toric intraocular lens (IOL) implants serving as the cornerstone intraoperative modality for effective correction. Successful outcomes depend on careful preoperative assessment and metic [....] » Read More
Leber Hereditary Optic Neuropathy (LHON) is a rare, maternally inherited mitochondrial genetic disorder characterized by sudden, painless vision loss. The disease has a significant unmet medical need and is primarily caused by three mitochondrial DNA point mutations: G3460A, G117 [....] » Read More
Several neurodegenerative diseases, including glaucoma, diabetic retinopathy, and age-related macular degeneration all involve retinal cell death. Reliable experimental models of such diseases are important for developing novel therapeutic strategies and for assessing the efficac [....] » Read More
Introduction: Anaemia is one of the most common medical complications in pregnancy, affecting over 40% of pregnant women globally, with iron deficiency accounting for 90-95% of cases. It is associated with serious maternal risks—such as fatigue, preterm labour, and postpart [....] » Read More
The convergence of artificial intelligence (AI) and vision is not merely a contemporary phenomenon but is deeply rooted in the shared origins of both disciplines. This paper traces the evolution of this intersection, from the pioneering neurophysiological research of Hubel and Wi [....] » Read More
Topic: This scoping review synthesizes existing evidence on the ocular health status of homeless or marginally housed (HMH) adults, highlighting the prevalence of visual impairment, ocular pathologies, and barriers to accessing care. Clinical Relevance: HMH adults are disproport [....] » Read More
Background: Declining confidence in ophthalmology among junior doctors suggests a gap in the medical school curriculum (Scantling-Birch et al., 2022). Limited GMC guidance (Kanagasundaram et al., 2025) and discrepancies (Devine, O et al., 2020) between undergraduate teaching wors [....] » Read More
Background: Declining confidence in ophthalmology among junior doctors suggests a gap in the medical school curriculum (Scantling-Birch et al., 2022). Limited GMC guidance (Kanagasundaram et al., 2025) and discrepancies (Devine, O et al., 2020) between undergraduate teaching wors [....] » Read More
Introduction: This case report discusses a patient presenting with elevated intraocular pressure (IOP) unresponsive to oral or intravenous treatment, necessitating urgent cyclodiode intervention. Initial investigations revealed the possibility of either uveal melanoma or supracho [....] » Read More
Introduction: NHS cataract service delivery has been increasingly challenged by rising demand, resources constraints, the pandemic, and the expansion of independent sector providers (ISPs). This study aims to assess whether there has been a shift towards managing more non-routine [....] » Read More
Background: Non-infectious uveitis encompasses a spectrum of intraocular inflammatory diseases involving the uveal tract, retina, vitreous, and optic nerve. Complications such as cystoid macular oedema (CME), cataract, and secondary glaucoma contribute to nearly 10% of legal [....] » Read More
Aim: To evaluate the impact of the Iluvien implant on patient-reported quality of life in individuals with macular oedema. This study assessed changes in health status across functional, psychological, and visual domains using the EQ-5D-5L and EQ-VAS instruments. Methods:&n [....] » Read More
Introduction: Cataract is the leading cause of reversible blindness worldwide, responsible for approximately 45% of global blindness and affecting over 65 million people. The burden is greatest in low and middle-income countries, where access to timely surgery is often limit [....] » Read More
Introduction: Diabetes Mellitus affects over 4.6 million adults in the UK; 90% will develop diabetic retinopathy (DR) within 20 years of diagnosis. Diabetic eye screening (DES) is vital for the early detection and effective management of DR. R4 is referable retinopathy (prolifera [....] » Read More
Aims: Newborn eye screening is a non-invasive and vital tool for detecting serious ocular conditions such as congenital cataracts, retinoblastoma, congenital glaucoma. Eye development is complex, and can be affected by genetic, infective and environmental factors. Prompt identifi [....] » Read More
Introduction: Artificial intelligence (AI) has transformed medicine, with various applications across diagnostics and clinical decision tools that have been applied in many specialties, including ophthalmology. Systems that use AI have been implemented to identify retinal disorde [....] » Read More
Introduction: Red eye is a frequent presentation in primary care, where most cases are benign but some may threaten sight. Limited access to specialist tools can make distinguishing serious pathology difficult. The NICE guidelines highlight five “red flag” sympto [....] » Read More
Background: Most deep learning systems for diabetic retinopathy (DR) screening rely on architectures such as ResNet and EfficientNet, with recent attention shifting towards transformer-based models. However, less is known about whether modernised convolutional backbones alon [....] » Read More
Introduction: Idiopathic elevated episcleral venous pressure (IEEVP), also known as Radius-Maumenee syndrome, is a rare condition characterized by dilated episcleral veins and open angle glaucoma. It can pose a diagnostic and management challenge for clinicians, often necess [....] » Read More
Background: Ophthalmology remains one of the highest-volume surgical specialties worldwide, with more than one million procedures performed annually in England alone. Never events (NEs), though rare, are high-impact, preventable incidents, and can have significantly negative co [....] » Read More
Introduction: Metastatic uveal melanoma (mUM) is a rare, aggressive malignancy with limited responsiveness to conventional chemotherapies. Immune checkpoint inhibitors (ICIs)—including Ipilimumab, pembrolizumab, nivolumab, and dual-agent regimens—have emerged as [....] » Read More
Objective: Persistent anterior uveitis (PAU) following uncomplicated cataract phacoemulsification surgery is a rare but clinically significant complication. This retrospective observational study evaluates PAU persisting beyond 12 months in an ethnically diverse (Global Majo [....] » Read More
Modern anti–vascular endothelial growth factor (VEGF) agents, including aflibercept 8 mg (Eylea HD) and Faricimab (Vabysmo), have shown promise in extending treatment intervals while maintaining or improving visual acuity in chronic retinal diseases such as neovascular ag [....] » Read More
The management of irregular corneas remains one of the most demanding challenges in modern contact lens practice. While traditional approaches may provide partial solutions, the advent of advanced imaging technologies and freeform lens design software has opened new possibiliti [....] » Read More
Diabetic retinopathy (DR) and glaucoma cause pre ventable blindness in over 600 million people worldwide. Early detection is critical, but challenging due to limited specialist access. We present BioTwinXAI-Eye, a digital twin system that creates a virtual model of each patient&r [....] » Read More
Purpose: To investigate the correlation between corneal biomechanical characteristics and refractive status in children.Methods: A cross-sectional study involved 339 children aged 5 to 13 with spherical equivalent range from -6.00D to +2.00D. Axial length was measured by IOL Mast [....] » Read More
This presentation addresses the management of cicatricial ectropion, a condition caused by excessive scarring secondary to trauma, thermal, or chemical burns etc. The primary treatment approach discussed involves identifying and releasing cicatricial forces and harvesting full-th [....] » Read More
Purpose: To evaluate visual and clinical outcomes in patients with endogenous endophthalmitis (EnE) undergoing early pars plana vitrectomy (PPV) versus intravitreal antibiotics and biopsy alone (IOAB). Methods: This retrospective study was conducted at a tertiary eye [....] » Read More
Purpose: To report an unusual case demonstrating overlapping features of idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) and Eales' disease, highlighting the diagnostic challenges in atypical retinal vasculitis. Methods: A 31-year-old male pr [....] » Read More
Caffeine is a substance that people use in a variety of forms and in varying amounts in their daily life all around the world. Accommodation is the ability of Eye’s to adjust its focus on objects at varying distances, plays a vital role in visual acuity and overall eye func [....] » Read More
Aggressive retinopathy of prematurity (A-ROP) is characterized as the most severe form of the disease, with a fulminant course and the development of volcano-shaped retinal detachment, most commonly occurring in extremely preterm infants. Among disabling conditions in preterm neo [....] » Read More
Aim: To evaluate the anatomical and refractive outcomes in patients with type 1 retinopathy of prematurity in zone 1. Materials and methods: The study included 77 preterm infants (154 eyes) between 2020 and 2025 and analyzed retrospectively and prospectively. Patient [....] » Read More
Introduction: Big Data and AI are transforming ophthalmology, particularly in the early detection of diabetic retinopathy (DR). Leveraging vast datasets and machine learning, these technologies enhance diagnostic accuracy and accessibility. However, ethical concerns regardin [....] » Read More
Background: Immunodeficiency is associated with increased susceptibility to infection; however, its role as a potential risk factor for post-operative endophthalmitis (POE) following elective cataract extraction (CE) remains unclear. Current clinical guidelines do not recomm [....] » Read More
Background: Diabetic retinopathy (DR) is a serious complication of diabetes mellitus (DM). MicroRNAs (miRNAs) play crucial roles in DR pathogenesis, but their expression patterns across different DR stages remain unclear. Objective: To investigate the expression leve [....] » Read More
Extramedullary multiple myeloma is a rare and aggressive manifestation of multiple myeloma, with limited cases involving concurrent intraocular, orbital, and intracranial plasmacytomas. We report a 59-year-old female veteran diagnosed with multiple myeloma who presented with wors [....] » Read More
Background: Rubeosis iridis, characterized by neovascularization of the iris and anterior chamber angle, presents significant clinical risks including neovascular glaucoma, vision loss, and ocular discomfort. Timely diagnosis and intervention are critical components of effective [....] » Read More
Background: As patients increasingly turn to digital platforms for medical information, the role of artificial intelligence (AI) tools such as ChatGPT and DeepSeek in patient education is expanding. However, concerns remain regarding the readability, accuracy, and overall quali [....] » Read More
This poster presents an evaluation of a student-led ophthalmology conference, exploring its educational impact, accessibility, and influence on medical students’ career considerations. The study examined the SCRUBS National and Regional Ophthalmology Conference held in Marc [....] » Read More
Background: IgG4-related disease (IgG4-RD) is a chronic, immune-mediated fibroinflammatory condition recognized as a multisystem disorder, often presenting with organomegaly, fibrosis, and organ dysfunction (1,2,10). Histopathologically, it is characterized by dense lympho [....] » Read More
Ophthalmology is entering a transformative era fueled by groundbreaking advances in computational medicine, genomic technologies, and multidisciplinary research. These innovations hold immense potential to revolutionize diagnostics, treatment, and long-term care in vision science [....] » Read More
Background: Nevus of Ota, also known as oculodermal melanocytosis (ODM), is a congenital or acquired condition characterized by the proliferation of dermal and uveal melanocytes, leading to hyperpigmentation of periocular skin, sclera, and intraocular structures. Although benig [....] » Read More
Background: Myopia prevalence among schoolchildren is rising, and axial elongation (AL) is associated with increased risks of myopic macular degeneration, glaucoma, and retinal detachment. Defocus Incorporated Multiple Segments (DIMS) spectacle lenses induce peripheral myopi [....] » Read More
Optogenetic therapy holds great potential for treatment of late-stage photoreceptor degenerative diseases. However, clinical translation of such therapeutic candidates is usually impeded by inconsistency in evaluation of visual function between preclinical models and clinical pra [....] » Read More
Introduction: Choroidal osteoma is a rare, benign ossifying tumor characterized by mature bone formation within the choroid. It typically affects young women, is usually unilateral, and may lead to significant visual morbidity due to complications such as choroidal neovasc [....] » Read More
Background: Minimally invasive glaucoma surgery (MIGS) has been adopted worldwide for the surgical treatment of primary open angle glaucoma (POAG). However, more studies are needed comparing the long-term efficacy of different procedures. Aims and objectives: Long-te [....] » Read More
Background: Acute Lymphoblastic Leukemia (ALL) is the most common childhood malignancy, while ocular involvement in leukemia is not uncommon, However, severe anterior segment findings such as acute onset proptosis with chemosis-induced exposure keratopathy are rare and under [....] » Read More
Objective: To investigate the association between physical development indicators and peripheral axial length(PAL), retinal radius of curvature in school-age children. Methods: A case series study. From March to July 2025, 334 school-age children(334 eyes) treated in the [....] » Read More
Background: Glaucoma is the leading cause of irreversible blindness worldwide. Early detection remains challenging due to subtle clinical sings and limited access to advanced diagnostic tools. Artificial lntelligence (AI) has emerged as a promising solution; however, few studies [....] » Read More
Title : Storytelling to cure blindness: A digital implementation lab to expand global ophthalmology training awareness and philanthropy
Blake Marleau Snyder, Stanford Hospital and Clinics, United States
Background: Preventable blindness remains one of the most solvable global health inequities, yet public awareness, trainee engagement, and philanthropic participation remain disproportionately low. At the same time, digital creators have demonstrated an unprecedented ability to [....] » Read More
Title : Rare and interesting case of Goldenhar’s syndrome in a 3 years old male child
Gowhar Ahmad, Florence Hospital Srinagar, India
It was an Austrian ophthalmologist, Maurice Goldenhar, who in 1850 first described a syndrome complex characterized by congenital presence of limbal dermoid with congenital associated presence of preauricular skin tag or appendage. Sometimes, there is presence of squint, anophtha [....] » Read More
Title : Comparative outcomes of a newly modified trabeculectomy versus conventional trabeculectomy
Hyungju Park, Gangnam Tokyo Eye Clinic, Korea, Republic of
This prospective comparative study evaluated the outcomes of a newly modified trabeculectomy (NMT) versus conventional trabeculectomy (trab) in patients with open?angle glaucoma, with a special interest in its usefulness for normal-tension glaucoma. A total of 121 eyes were an [....] » Read More
Title : Factors associated with primary open angle glaucoma in a Nepali population Jiri Eye Study: Oculo genetic study
Archana Sharma, Tilganga Institute of Ophthalmology, Maldives
Introduction: Glaucoma is the second most common cause of blindness with primary open-angle glaucoma (POAG) as one of the leading causes. Objective: To study the ocular and systemic associated factors that lead to the development of primary open-angle glaucoma Methodology: [....] » Read More
Title : Evaluating the quality and readability of AI chatbot responses to frequently asked questions on basal cell carcinoma: Implications for patient education and digital health communication
Arrane Selvamogan, Leicestershire Partnership NHS Trust, United Kingdom
Background: Artificial intelligence (AI)-powered chatbots are increasingly used to deliver health information, providing real-time, accessible responses to patient queries. Concerns persist about the clarity, accuracy, and credibility of AI-generated medical content, especia [....] » Read More
Title : Evaluating the quality and readability of AI generated ophthalmic surgery education: A four model comparison
Arrane Selvamogan, Leicestershire Partnership NHS Trust, United Kingdom
Background: Artificial intelligence (AI) tools, particularly large language models (LLMs), are increasingly utilised to provide health information, with patients seeking simplified explanations of surgical procedures. In ophthalmology, the readability and reliability of AI-g [....] » Read More
Title : Evolving strategies in tissue procurement preservation and distribution to maximize corneal tissue utilization a fifteen year experience
Valentin Junger, University of Rome "Tor Vergata", Italy
Background: The paradigm of corneal transplantation has rapidly transitioned from penetrating keratoplasty (PK) to lamellar (e.g., DALK, ALK) and endothelia ltechniques (e.g., DMEK, DSAEK). Successful eye banking requires continuous adaptation in tissue preparation and preservati [....] » Read More
Title : Relationship between tear meniscus parameters and nasal anatomy: Does nasal septum deviation affect tear parameters?
Bilgehan Erduran, Malatya State Hospital, Turkey
Purpose: To investigate whether nasal anatomical alterations associated with nasal septum deviation (NSD) contribute to early functional impairment in the lacrimal drainage system, potentially indicating subclinical stages of primary acquired nasolacrimal duct obstruction (PANDO) [....] » Read More
Title : SUMOylation is a translatable target in hypoxic MNPs regulating retinal vasculopathy
Xufang Sun, Huazhong University of Science and Technology, China
Retinal vasculopathies pose devastating threat to human health. While anti-VEGF therapy situates the first-line treatment for patients, the clinical efficacy is limited by suboptimal response and potential risks raised by the long-term high-dosage use. Neurovascular unit (NVU) un [....] » Read More
Title : Experimental study on the effect of PINK1 mediated mitophagy on diabetic retinal neuroglial network lesions
Xiangxia Luo, Gansu University of Chinese Medicine, China
Objective: To explore the role of mitophagy in diabetic retinal neuroglial network lesions and analyze its mechanisms. Methods Experimental study. SD rat retinal müller cells (rMCs) were cultured in vitro, and the cells were divided into control (Control), hyperosmosis (HP), [....] » Read More
Title : Clinical research on the efficacy of yishi mingmu pills combined with yishi tongluo exercises in the prevention and control of myopia in children and adolescents
Xiangxia Luo, Gansu University of Chinese Medicine, China
Objective: To evaluate the efficacy of Yishi Mingmu Pills (a traditional Chinese medicine formulation) combined with Yishi Tongluo Exercise (a modified eye exercise) in children with early myopia and mild myopia due to deficiency of heart yang. Methods: A randomised controlled [....] » Read More
Title : Minimally Invasive Glaucoma Surgery (MIGS) with iStent inject W in Primary Open-Angle Glaucoma (POAG): Clinical outcomes and best practices
Peng Lu, The Second Hospital of Lanzhou University, China
Object: Primary open-angle glaucoma (POAG) remains a leading cause of irreversible blindness, with minimally invasive glaucoma surgery (MIGS) emerging as a pivotal strategy for early-stage management. This study aims to evaluate the clinical outcomes and safety of iStent Inject W [....] » Read More
Title : Intravitreal dexamethasone implant versus ranibizumab versus ranibizumab combined with dexamethasone implant for macular edema secondary to retinal vein occlusion
Xiubin Ma, Qingdao Eye Hospital of Shandong First Medical University, China
Purpose: To compare the efficacy of intravitreal injection (IV) ranibizumab, ranibizumab plus dexamethasone implants (R + DEX), and DEX for macular edema secondary to retinal vein occlusion (RVO-ME). Methods: This was a double-blinded, randomized, comparative study. Two hundre [....] » Read More
Title : Pattern of uveitis in a secondary eye care center at Panipat Haryana
Kritika Garg, HV Desai Eyecare Center Pune, India
Background: Uveitis pattern varies according to regional, demographic, and racial factors. Therefore, an epidemiological study of the distribution of uveitis in various regions in India is likely to provide valuable information. There is no study available on the pattern of uveit [....] » Read More
Title : Intra orbital wooden foreign bodies: A retrospective study of 30 cases
Chandana Chakraborti, Regional Institute of Ophthalmology, Medical College & Hospital, India
We aimed to study thirty consecutive cases of intraorbital wooden foreign body (IOWFB), their clinical profile, and management in a tertiary care hospital. Materials and method: A retrospective observational study of 30 cases at our center from March 2020 to December [....] » Read More
Title : Amyloid associated protein misfolding and structural alterations in human cataractous lenses
Sujata, Indian Institute of Technology Kanpur, India
Cataract, opacification of the lens, is a multifactorial eye disease affecting millions of people globally. However, its underlying etiology remains unclear despite progress in surgical methods. Although researchers have implicated oxidative stress and post- translational modific [....] » Read More
Title : Managing milky capsular bag distension with inferior laser capsulotomy not the usual cut
Pooja Bansal, Centre for Sight Eye Institute, India
A 60-year-old man presented with recent onset decrease in vision in the right eye (OD). Both eyes (OU) had undergone uncomplicated cataract surgery ten years back. Best corrected visual acuity OD was 20/60 and 20/400 in the left eye (OS). Slit lamp examination revealed a normal [....] » Read More
Title : Multimodal imaging characteristics of fibrinous central serous chorioretinopathy masquerading posterior uveitis
Pooja Bansal, Centre for Sight Eye Institute, India
Retrospective study of records of 8 patients (12 eyes) of fibrinous CSCR, misdiagnosed as posterior uveitis elsewhere. Fundus images, fluorescein angiography (FA), autofluorescence and optical coherence tomography (OCT) at baseline and follow up visits were analyzed. Minimum du [....] » Read More
Title : Retinitis pigmentosa misdiagnosed as retrobulbar neuritis
Vidush Ratan, Deen Dayal Upadhyay Hospital, India
Case: Female of 17 years of age ,resident of delhi belonging to lower middle socioeconomic status;chief complaints: diminution of distant vision since childhood and headache since last one year;history of present illness: complaints of diminision of vision since childhood espec [....] » Read More
Title : Common and uncommon ocular and facial indications of Botox: Clinical insights supported by illustrative videos
Ashwini Meherda, VMMC & Safdarjung Hospital, India
Botulinum toxin type A (Botox) is an established neuromodulator widely utilized in ophthalmology and facial aesthetic practice. By inhibiting presynaptic acetylcholine release at the neuromuscular junction, it produces reversible chemo denervation and targeted muscle relaxation. [....] » Read More
Title : Sac swelling doesn’t regurge: No time to relax
Rishav Raj, Dr Rajendra Prasad Centre for Ophthalmic Sciences, India
Objective: Lacrimal sac tumors are extremely rare. Most common benign tumor being squamous papilloma. Herein we present two unusual cases of benign lacrimal sac tumors with aim to highlight their clinical features and di [....] » Read More
Title : Barriers to essential eyecare service by visually impaired people and the impact of war in fragile conflict affected tigray region Ethiopia
Abeba Tesfay Gessesse, Mekelle University, Ethiopia
Background: Ethiopia faces a high burden of blindness and visual impairment, yet access to eyecare services remains limited, particularly in conflict-affected areas like Tigray. The two-year long war in Tigray has devastated healthcare infrastructure, further exacerbating [....] » Read More
Title : Visual functions and anterior ocular surface changes post-trans-epithelial photo refractive keratectomy
Elnzeer Hussain Essa Mohammed, My Sight Optical, Sudan
Purpose: To assess the impact of Trans-PRK on visual acuity, contrast sensitivity, spherical aberration, tear stability, corneal surface and thickness. Method: A quantitative, comparative, and prospective case study was conducted in the Kingdom of Saudia Arabia after receiving [....] » Read More
Title : Corneal blindness can be prevented right decision right action is the need of the hour
Kandagadla Jyoti, MTMC, India
Introduction: Corneal blindness accounts to 3.2 to 5.1 % of all cases of blindness worldwide. A wide variety of diseases and conditions can cause corneal blindness. In this presentation I would like to summarise the various causes, methods to prevent them and the role o [....] » Read More
Title : Tiny eyes big battles rare case of 4 months old
Trupti Sute, Government Medical College, India
Retinoblastoma is the most common ocular malignancy of childhood. Although retinoblastoma primarily affects younger children, it is very rare below 1 year of age. A 4-months-old girl child presented with leukocoria in her right eye since 2 months. Posterior segment examination re [....] » Read More
Title : Unravelling an ABHD12 mutation: a genetically confirmed case of PHARC syndrome
Priyanka Shinde, Shroff's Charity Eye Hospital, India
Purpose: The purpose of this case report is to highlight the clinical heterogeneity and diagnostic challenges of PHARC syndrome, a rare autosomal recessive neurodegenerative disorder caused by ABHD12 gene mutations. By presenting this report, we highlight the value of multis [....] » Read More
Title : Insights into a solution for post refractive surgery Ectasia
Rubina Shah, National Eye Center Lahore, Pakistan
Introduction: In the recent decade, technological advancements in ophthalmology have made procedures more precise for both patients and surgeons. However, it also has detrimental side effects if used without proper research. Post-lasik ectasia is a devastating side effect after a [....] » Read More
Title : Dry eye disease in the context of refractive surgery: Prevalence metrics and treatment outcomes among military personnel
Sevinj Orujova, Azerbaijan Medical University, Azerbaijan
The study included 185 military personnel indicated for refractive surgery. Group I (n=90) with preoperative mild dry eye disease (DED) confirmed and managed with standard ocular-surface therapy and Group II (n=95) without indication for preoperative DED treatment. Postoperativel [....] » Read More