Purpose: To find the difference between the planned ablation depth (given by the laser manufacturer) and the measured reduction in corneal stroma thickness in the ablation area. Setting: Memira Eyecenter, Tromsø Methods: Prospective study of 40 eyes of 40 patients un [....] » Read More
A forty-eight-year-old male of Indian descent with a haematological malignancy on systemic immunosuppression presented with reduced vision in both eyes approximately 8 weeks following commencement of Ibrutinib. His medical history is complex with recent changes to medication, new [....] » Read More
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the aetiological agent of the most dramatic pandemic of the new millennium, the well-known Coronavirus Disease 2019 (COVID-19). It is characterized by many clinical-pathological facets, which can be summarized as fol [....] » Read More
Methodology: A multi-centered cross sectional study was conducted from January 2022 to July 2022. 250 people between the ages of 40 and 65 were recruited using a non-probability purposive sampling technique. Mild (up to 3D) , moderate( 3D to 6D) and severe degree (mor [....] » Read More
Background: Diabetes mellitus is a common metabolic disorder which is characterized by elevated blood sugar level. It is a major cause of blindness in our country, which is preventable and treatable, if healthy practise and knowledge regarding this disease is applie [....] » Read More
Currently, additive keratoplasty is a practically useful method in keratoconus, hyperopia, and reduction of tube exposure. It is called CAIRS, corneal allogeneic intrastromal ring segments; FAISCG, Femtosecond-assisted intrastromal corneal graft; FLEx, Femtosecond Lenticule Extr [....] » Read More
The management of refractory glaucoma remains a challenge for the ophthalmologist today. Despite a literature rich in clinical studies, there is no consensus for its management.The multitude of possible treatments undoubtedly reflects the complexity and etiological heterogeneity [....] » Read More
PANIS method (Plasma Assisted NonInvasive Surgery) is about treatment of more than 15 ocular surface diseases with just one device using plasma technology. But the difference between PANIS and past modalities which attracts ophthalmologists all over the world is that, this novel [....] » Read More
Purpose: Corneal ulcer is one of the important ophthalmic condition causing significant morbidity especially in the developing countries. Bacteria and fungi are frequently responsible for suppurative corneal ulcers especially in the developing countries.The present study aim [....] » Read More
Dr Carolina Mercado started her career in Ophthalmology as pre-residency research fellow at Bascom Palmer Eye Institute. She has published more than 20 research articles in SCI(E) journals focused on Ocular Surface tumors and Regenerative medicine of the cornea. In 2019 she joine [....] » Read More
Background : Orbital Venolymphatic Malformations (OVLMs) are rare, benign cystic vascular malformations. Materials and Methods : A retrospective study of treatment modalities for OVLM in 20 patients was studied over 2 years at a Tertiary Eye Care Centre. They were categorised [....] » Read More
Background: Mucormycosis is a deadly opportunistic fungal infection characterized by direct invasion with marked tissue necrosis of adjacent structures followed by rapid progression and angioinvasion from the nasal and sinus mucosa into the orbit and brain. It has been an increas [....] » Read More
Objective To compare air versus gas tamponades in pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD). Introduction Rhegmatogenous retinal detachment (RRD) is the most common type of retinal detachment involving full-thickness retinal breaks in the ne [....] » Read More
Title: Rapid Fire Round: Management of challenging cases in pediatric ophthalmology and Strabismus Purpose: To highlight the variety of presentations, assessment and management of challenging cases in pediatric ophthalmology. Special attention was given to the squi [....] » Read More
Aim: Previous studies assessed the ocular surface integrity and tear stability are climate dependent. Although previous prevalence studies of Keratoconjunctivitis Sicca (KCS) associated with air pollutants were reported from some countries worldwide, there is no uniform conclusio [....] » Read More
PURPOSE : To report a case presented to tertiary care center of neuromyelitis optica CASE REPORT: we described a case of neuromyelitis optica a 28 years old female presented to our hospital with complaints of diminution of vision in right eye since 35 days. History of cough, [....] » Read More
Background: Pyogenic granuloma(PG) is a benign vascular proliferation of immature capillaries, leading to a lobular lesion. It is a misnomer, as it is neither purulent in nature nor of granulomatous variety. Ocular PG usually arises from conjunctiva and eyelids. Predisposing [....] » Read More
The current study aims to compare outcomes of diclofenac versus corticosteroids following strabismus surgery. A systematic review and meta-analysis were performed in line with the PRISMA guidelines. An electronic search was performed to include comparative studies of diclofenac v [....] » Read More
BACKGROUND: Cataracts, diabetic retinopathy, and peripheral neuropathy share a common pathophysiology: osmotic damage from sorbitol buildup. Over a lifetime, metabolism of glucose results in sorbitol buildup in certain tissues (lens, retina, Schwann cells) that have limited amoun [....] » Read More
Introduction: Measurement of intraocular pressure (IOP) is critical for the management of glaucoma. The current gold standard measurement apparatus is the Goldmann Applanation Tonometer, a tool which utilizes the Imbert-Fick Principle where intraocular pressure equals the contact [....] » Read More
Title : Lumevoq gene therapy in leber hereditary optic neuropathy
Magali Taiel, GenSight Biologics, France
Leber hereditary optic neuropathy (LHON) is a rare, maternally inherited mitochondrial genetic disease with a continued high unmet medical need. Three primary point mutations in the mtDNA are responsible for LHON in approximately 90% of subjects: G3460A, G11778A and T14484C, loca [....] » Read More
Title : The Living Bleb. Clinical Application of Cytokines and Bleb Survival
Jeffrey Freedman, Professor Emeritus SUNY Brooklyn, United States
The pathophysiology of blebs, in relation to glaucoma implant surgery, and the reasons for success or failure of the blebs will be presented. The importance of intraocular pressure on the success of the bleb will be emphasized.The presentation will discuss the mechanisms whe [....] » Read More
Title : Onchocerciasis elimination from the America´s
Jose Roberto Proano Santana, Member of Ecuadorian Medicine Academy, Ecuador
Onchocerciasis is filariasis whose greatest morbidity affects the eyes causing blindness. It is found geographically in fast-flowing rivers. The continent that is the most affected is Africa and it is also found in 31 countries, becoming endemic. The parasite is Onchocerca volvul [....] » Read More
Title : Insights into the treatment of Idiopathic Intracranial Hypertension with an LP or temporary lumbar drain
Peter Colin Gates, Deakin University Waurn Ponds, Australia
Six cases that provide insights into the pathophysiology of IIH and a new approach to management will be discussed. Four developed a low-pressure headache, 2 after an LP, 1 with a malfunctioning lumbo-peritoneal(L-P) shunt, 1 with a malfunctioning ventriculo-peritoneal (V-P) shun [....] » Read More
Title : Identifying diabetes from conjunctival images using a novel hierarchical multi-task network
Xinyue Li, Shanghai Children ‘s Hospital, China
Diabetes can cause microvessel impairment. However, these conjunctival pathological changes are not easily recognized, limiting their potential as independent diagnostic indicators. Therefore, we designed a deep learning model to explore the relationship between conjunctival feat [....] » Read More
Title : Fundus changes evaluated by OCTA in patients with cerebral small vessel disease and their correlations: A Cross-Sectional study
Yongzhe Gu , Tongji University, China
Objective: To detect fundus changes in patients with cerebral small vessel disease (CSVD) using optical coherence tomography angiography (OCTA) and to investigate the correlations between CSVD and fundus changes. Methods: From January 2019 to January 2020, patients diagnosed with [....] » Read More
Title : IOLCon – the roadmap for reliable IOL calculation. New features of modern international internet data-base for updated and optimized IOL constants: The “Lens Power Calculation Module.
Sibylle Scholtz, Institute of Experimental Ophthalmology, Germany
Purpose: The Internet database IOLCon (www.iolcon.org), founded in 2017, established itself meanwhile as a reliable, worldwide available source for optimized IOL constants and specifications. Based on modern optimization strategies, IOLCon also offers individually optimized IO [....] » Read More
Title : A case of ‘60-day glaucoma’
Jagruti Godhaniya, United Lincolnshire Hospitals NHS Trust, United Kingdom
Introduction: Neovascular glaucoma (NVG) has been called ‘90-’ or ‘100-day glaucoma’ in the past due to its typical development 3 months after the onset of central retinal vein occlusion (CRVO). In reality, NVG can occur anywhere between 2 weeks and 2 year [....] » Read More
Title : The usual suspects: Bilateral astrocytic hamartomas in tuberous sclerosis
Nishi Meghna Satish, VMMC & Safdarjung Hospital, India
The objective of this clinical case report is to stress upon the importance of careful clinical examination in patients of Tuberous sclerosis. We present three cases out of which two had very prominent retinal hamartomas and one patient had inconspicuous small hamartomas in the p [....] » Read More
Title : A rare case of weding arc maculopathy
Kshitij Suchit Tamboli, Tamboli Hospital, India
I, hereby report a rare case of welders arc maculopathy in a 22-year-old patient professional welder working for 4 years as welder came with bilateral, symmetrical decrease in the visual acuity since 1 month. Fundus revealed dull foveal reflex (OU) with subtle foveal alterations [....] » Read More
Title : Fluorescent and Biocompatible Nitrogen and Sulfur Co-Doped Carbon Nanodots as an Ocular Fundus Angiography Imaging Agent
Burak Erdem, Ordu University, Turkey
Purpose: Fundus angiography (FA) imaging is limited by the drawbacks of standard fluorescein dye, including a narrow excitation spectrum, a non-uniform spectral emission pattern, photobleaching, and kidney toxicity. Carbon dots (CDs) nanoparticle may be a feasible alternative to [....] » Read More
Title : Morphological and functional assessment of filtering blebs on anterior segment optical coherence tomography
Anuradha Raj, All India Institute of Medical Sciences, India
Glaucoma has been surgically treated by various surgical procedures and one of them is trabeculectomy. Bleb morphology in addition to various characteristics by classification systems is an important clinical parameter that indicates bleb function and predicts bleb-related compli [....] » Read More
Title : A case of late onset Stargardts disease
Kshitij Suchit Tamboli, Tamboli Hospital, India
I, hereby report a case of late-onset Stargardt's disease in a 51-year-old patient who came with bilateral, symmetrical decrease in the visual acuity . Stargardt disease is the most common form of juvenile macular degeneration. Clinically, it is characterized by pisciform fle [....] » Read More
Title : Extended Depth of Focus versus Trifocal for Intraocular Lens Implantation: An Updated Systematic Review and Meta Analysis
Mohammad Karam, AlBahar Ophthalmology Center, Kuwait
Objective To compare the outcomes of extended depth of focus (EDOF) versus trifocal intraocular lenses (IOLs) in patients undergoing cataract surgery. Methods A systematic review and meta-analysis were performed as per the Preferred Reporting Items for Systematic Reviews [....] » Read More
Title : Intravitreal Diclofenac Versus Intravitreal Bevacizumab in Diabetic Macular Edema: Systematic Review and Meta-Analysis
Mohammad Karam, AlBahar Ophthalmology Center, Kuwait
Aim To compare the outcomes of intravitreal diclofenac (IVD) versus intravitreal bevacizumab (IVB) in diabetic macular edema (DME). Methods A systematic review and meta-analysis were performed as per the Preferred Reporting Items for Systematic Reviews and Meta-analyses [....] » Read More
Title : Effect of Mesenchymal Stem Cell-derived Extracellular Vesicles (EVs) on Cornea Nerve Regeneration
Elmira Jalilian, University of Illinois at Chicago, United States
Purpose: Corneal nerves and innervation are susceptible to several diseases including diabetes. Despite the clinical need to promote corneal nerve regeneration, few specific therapeutic interventions are available. MSCs and their paracrine effect mediated by EVs presents an attra [....] » Read More