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4th Edition of

International Ophthalmology Conference

March 05-07, 2026 | Singapore

IOC 2025

Granulomatosis with polyangiitis-associated sclerokeratitis in a case of ocular adnexal B-cell lymphoma

Speaker at International Ophthalmology Conference 2025 - Ghazal Valizadeh
Royal Brisbane and Women's Hospital, Australia
Title : Granulomatosis with polyangiitis-associated sclerokeratitis in a case of ocular adnexal B-cell lymphoma

Abstract:

We describe the first reported case of granulomatosis polyangiitis (GPA)-associated sclerokeratitis in a patient with treated ocular adnexal lymphoma (OAL). The patient presented with pain and decreased vision in the left eye over several weeks. Past medical history was significant for recent bilateral relapsing OAL that was treated successfully with radiotherapy. Examination of the eyes revealed sectoral scleritis and peripheral ulcerative keratitis. Magnetic resonance imaging (MRI) of the orbits excluded recurrence of OAL and serum antineutrophil cytoplasmic autoantibody (ANCA) titres confirmed the diagnosis of GPA. Disease was poorly responsive to systemic steroids, azathioprine and rituximab. Ultimately, resolution was achieved with successive subconjunctival dexamethasone and subconjunctival triamcinolone injections. This case highlights the need to consider ocular inflammation in patients with a history of malignant hemopathies.

Biography:

Ghazal graduated medicine at Bond University in Queensland, Australia, in 2020. She then completed her Master of Medicine (Ophthalmic Science) at the University of Sydney in 2024. Currently working as a junior doctor at the ophthalmology department in Sunshine Coast University Hospital, Ghazal is committed to a career in ophthalmology and medical research. 

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