Ophthalmologists are always looking for new ways to provide better treatment to their patients. A key component of this search is the development of more accurate and efficient diagnostic instruments. Diagnostic procedures in ophthalmology have progressed significantly from the early stage of pars plana vitrectomy, when instrumentation and diagnostic tools were limited and the number of entities that could be diagnosed by invasive methods was limited. The application of new instruments has substantially improved eye care and treatment of common eye conditions. The ability to identify and treat eye problems, as well as the overall quality of eye care, will increase as new technologies are created.