Trabecular Meshwork

The trabecular meshwork is a crucial structure in the eye responsible for regulating the outflow of aqueous humor, maintaining intraocular pressure. Located near the angle where the iris meets the cornea, it consists of a network of trabecular beams and sheets lined by endothelial cells. These cells provide resistance to the aqueous humor as it drains from the anterior chamber into Schlemm's canal, ultimately exiting through collector channels into the venous circulation.

Dysfunction of the trabecular meshwork can lead to increased intraocular pressure, a hallmark of glaucoma. Conditions affecting the meshwork, such as pigment dispersion syndrome or pseudoexfoliation syndrome, can impair drainage and contribute to elevated pressure levels. Understanding the trabecular meshwork is crucial for managing glaucoma, as treatments often target improving aqueous outflow dynamics through this structure to alleviate pressure buildup and prevent optic nerve damage.