Limbus

In ophthalmology, the limbus refers to the border or junction between the cornea (the clear, dome-shaped surface covering the front of the eye) and the sclera (the white outer layer of the eye). This region is crucial because it houses stem cells responsible for maintaining the cornea's integrity and clarity. These limbal stem cells play a vital role in regenerating the corneal epithelium, which is essential for vision.

Disorders affecting the limbus, such as limbal stem cell deficiency (LSCD), can lead to impaired corneal healing, chronic inflammation, and vision loss. Treatment options for LSCD include transplantation of limbal tissue or stem cells from healthy eyes to restore function and improve visual outcomes. Understanding the limbus is thus fundamental in managing conditions that affect corneal health and vision, highlighting its pivotal role in ophthalmology.