Title : Corneal biomechanical characteristics and correlation analysis in children with different refractive states
Abstract:
Purpose: To investigate the correlation between corneal biomechanical characteristics and refractive status in children.Methods: A cross-sectional study involved 339 children aged 5 to 13 with spherical equivalent range from -6.00D to +2.00D. Axial length was measured by IOL Master; corneal biomechanical parameters by Corvis ST and Pentacam. According to SE, the subjects were divided into moderate myopia, mild myopia and emmetropia group. The correlation between AL, SE and corneal biomechanical parameters was analyzed. Results: A2V in the moderate myopia group was lower than that in both mild and emmetropia group (P<0.001). PD in emmetropia group was lower than that in mild (P<0.05) and moderate group (P<0.01). SSI in emmetropia group was higher than that in the other two groups (P<0.001), and SSI in the mild group was higher than that in moderate group (P < 0.01). A2V in 11-13 years was lower than that in 5-7 and 8-10 years old group (P<0.01). PD in 11-13 years old group was higher than that in 8-10 and 5-7 years old group (P < 0.01). SSI in 5-7 years old group was higher than that in 8-10 and 11-13 years old group(P < 0.01). AL was positively correlated with PD, negatively correlated with SSI and A2V. SE was positively correlated with A2V and SSI, negatively correlated with PD.
Conclusions: Corneal stiffness decrease with increase of SE. The changes of SSI, PD and A2V can be predictors of myopia progression in children aged 5~13 years.
