Title : 5 year comparison of safety and efficacy of iStent G1 and KDB goniotomy in primary open angle glaucoma
Abstract:
Background: Minimally invasive glaucoma surgery (MIGS) has been adopted worldwide for the surgical treatment of primary open angle glaucoma (POAG). However, more studies are needed comparing the long-term efficacy of different procedures.
Aims and objectives: Long-term comparison of efficacy and safety of iStent (G1) and KDB goniotomy, combined with phacoemulsification + IOL, through to 5 years.
Methods: A retrospective, real world, non-randomised, comparative study. Single centre. Primary outcome measure was number of cases achieving 20% or more IOP reduction from baseline; secondary outcome measures were change in drop dependence visual field mean deviation (VFMD) through to 5 years and adverse events.
Results: There were no significant differences in IOP reduction, number of cases achieving 20% reduction in IOP or VFMD at each time point through to 5 years. At each time point, the KDB group achieved significantly less drop dependence (p<0.001). There was a low rate of adverse events, and no cases of serious adverse events.
Conclusions: There was long-term success with each device with few transient adverse effects. The only difference between groups was the reduction in drop dependence that was immediate and persistent for the entire follow-up period in favour of KDB goniotomy.
