Title : Obstructive sleep apnoea in idiopathic intracranial hypertension: systematic review and meta-analysis
Abstract:
Aim
To determine the association between obstructive sleep apnea (OSA) and idiopathic intracranial hypertension (IIH).
Methods
A systematic review and meta-analysis were performed per the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. A search of electronic information through MEDLINE, EMBASE, and Cochrane Library was conducted to identify all studies reporting the association between OSA and IIH. The primary outcome was the prevalence of OSA. A random effects model was used for the analysis.
Results
Of 1467 studies identified, six studies enrolling 241 patients were included. The pooled estimate of the proportion of OSA in patients with IIH was 0.46 (95% CI = 0.40 – 0.52, P < 0.05), suggesting a higher prevalence of OSA in the studied population. The heterogeneity among the studies was moderate (I2 = 66%, P = 0.01).
Conclusions
The authors identified a 46% prevalence of OSA in patients with IIH. Neuro-ophthalmologists should rule out OSA in patients with newly diagnosed IIH.
Keywords
Obstructive Sleep Apnoea; Idiopathic Intracranial Hypertension; Prevalence.
Audience Take Away:
- Few studies have assessed the association between OSA and IIH. This is the first systematic review and meta-analysis to determine the association between OSA and IIH.
- OSA has been associated with various ophthalmic conditions, such as
- Diabetic retinopathy
- Central serous retinopathy (CSR)
- Non-arteritic anterior ischemic optic neuropathy (NAION)
- Although the included evidence is limited to six studies assessing the association between OSA and IIH, the pooled results suggest that there is a 46% prevalence of OSA among the IIH population. Neuro-ophthalmologists should rule out OSA in newly diagnosed patients with IIH.
