2nd Edition of

International Ophthalmology Conference

October 19-21, 2023 | Online Event

IOC 2023

Zoha Mian

Speaker at International Ophthalmology Conference 2023 - Zoha Mian
University of Louisville, United States
Title : Iris prosthesis for uveitis related iris defects


Iris defects can cause glare and poor cosmesis that affects a patient’s quality of life. These defects may be caused by congenital etiologies like aniridia or acquired ones like trauma and intraocular surgeries. Iris prostheses, like the CustomFlex ArtificialIris by HumanOptics, were created to address these symptoms. The CustomFlex device is a stand-alone thin and foldable silicone colored implant that could be placed in either the capsular bag or the sulcus. Because the majority of iris defects requiring prosthetic use was secondary to trauma, congenital aniridia, and intraocular surgeries, our case report aims to describe usage of the CustomFlex in a patient with iris defects secondary to uveitis. Our patient presented with photophobia caused by bilateral diffuse iris atrophy with a history of herpes zoster ophthalmicus and underwent simultaneous iris prosthesis and intraocular lens implantation. The procedure improved his vision while reducing photophobia and glare. This case report shows how endocapsular implantation of the CustomFlex Artificial iris, along with cataract surgery, is feasible for patients with uveitis related iris defects.

Audience Take Away Notes:

This case reports examines a practical and innovative solution to improve vison associated with uveitis caused iris defects and photophobia. This may expand the scope of use for iris prosthesis paving the path for utilization in other inflammatory ocular conditions.


Zoha Mian is a third-year medical student at the University of Louisville School of Medicine. She attended the University of Cincinnati and graduated in 2020 with a Bachelor of Science in Medical Sciences and Minors in Political Science and Global Health Studies. Zoha completed this case report alongside Dr. Anthony Mai and Dr. Craig Chaya as a visiting medical student at Moran Eye Center in January 2023.